The infrapatellar fat pad, also known as Hoffa's fat pad, is a mass of adipose tissue located below the kneecap (patella) within the knee joint. It plays a role in providing cushioning and shock absorption during movement, as well as producing various cytokines and other molecules that may contribute to inflammation and pain in the knee joint. Research on the infrapatellar fat pad has focused on its potential involvement in various knee conditions, such as osteoarthritis, rheumatoid arthritis, and patellofemoral pain syndrome. Studies have investigated the role of the infrapatellar fat pad in the development and progression of these conditions, as well as potential treatment approaches targeting this tissue. Overall, research on the infrapatellar fat pad highlights its importance in knee health and the need for further investigation to better understand its role in knee function and pathology.